The best Side of cees dekker
The best Side of cees dekker
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Working with solitary-molecule optical and AFM imaging and force-spectroscopy techniques, we search for to unravel the mechanistic areas of the construction and dynamics of chromosomes. Our study pursuits include things like:
Our group studies bacterial mobile division and is particularly aiming to constitute a ‘bottom up biology’ in artificial cells which will autonomously divide. Our major curiosity lies in mobile division, chromatin framework, and spatial Handle.
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Non-equilibrium folding of unique DNA molecules recaptured up to a thousand situations inside of a good point out nanopore
De sterke polarisatie in de discussie rond schepping/evolutie en meer algemeen rond geloof/wetenschap lijkt helaas geen eind te kennen. Toch is er wel degelijk een heilzame middenweg, maar deze krijgt about het algemeen weinig aandacht. Dit boek kan hier wellicht verandering in brengen. Wie de geschiedenis van de relatie tussen geloof en wetenschap in duikt, komt tot verrassende inzichten. De moderne mens leeft fulfilled veel stereotypen die historisch niet verantwoord blijken te zijn. Afgezaagde typeringen als ‘Vroeger dachten we dat de
SMC complexes can go Bodily roadblocks bigger than their ring size, indicating a nontopological mechanism for DNA loop extrusion
We use nanofabricated microfluidic structures to sample spatial boundaries for microbes and biomimetic vesicles with reconstituted protein networks which assess the basic part of spatial confinement on the molecular and cellular level. Our projects involve the subsequent:
Example (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is revealed in grey, the rim of your pore is highlighted in crimson, in addition to a 3D rendering in the movement in the DNA rod is exhibited.
What if, in place of making use of common prime-down silicon electronics, transistors could be designed from the bottom up employing single organic and natural molecules as the switching aspects? This concept, which grew to become The premise of these days’s subject of molecular electronics, initial emerged from the 1970s.
Bulk-area coupling identifies the mechanistic connection in ceesdekker between Min-protein designs in vivo and in vitro
Tests pseudotopological and nontopological models for SMC-driven DNA loop extrusion from roadblock-traversal experiments
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2004, discovery of recent physics in translocation of DNA by way of nanopores; initial experimental analyze of ions conduction in nanofluidic channels; 1st electrochemistry with person one-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; initially electrical docking of microtubules on kinesin-coated nanostructures; 1st biophysics characterization from the mechanical Attributes of double-stranded RNA; and very first one-molecule examine of DNA translocation by a restriction-modification enzyme.